Switching Drugs
نویسندگان
چکیده
منابع مشابه
Splice-switching antisense oligonucleotides as therapeutic drugs
Splice-switching oligonucleotides (SSOs) are short, synthetic, antisense, modified nucleic acids that base-pair with a pre-mRNA and disrupt the normal splicing repertoire of the transcript by blocking the RNA-RNA base-pairing or protein-RNA binding interactions that occur between components of the splicing machinery and the pre-mRNA. Splicing of pre-mRNA is required for the proper expression of...
متن کاملAutomated determination of drugs in serum by liquid chromatography with column-switching. I. Separation of antiepileptic drugs and metabolites.
This is a fully automated system for determining six common antiepileptic drugs and two principal metabolites of carbamazepine in serum. It is based on "high-performance" liquid chromatography (HPLC), with column switching. TSKprecolumn BSA-ODS and TSKgel ODS-120A (both from Toyo Soda) were used as the precolumn and analytical column, respectively. The former contains octadecylsilyl resins trea...
متن کاملAntithyroid Drugs
The thionamide drugs, i.e. carbimazole and its metabolite methimazole (MMI), andpropylthiouracil (PTU) have extensively been used in the management of various forms ofhyperthyroidism over the past eight decades. This review aims to summarize different aspectsof these outstanding medications. Thionamides have shown their own acceptable efficacy andeven safety profiles in ...
متن کاملRisk of significant infection in rheumatoid arthritis patients switching anti-tumor necrosis factor-α drugs.
OBJECTIVES To describe rates of first significant infection of rheumatoid arthritis patients who switch between anti-tumor necrosis factor (aTNF) drugs. METHODS Subjects with rheumatoid arthritis who received only aTNF drugs were observed in an insurance claims database from January 2001 to December 2007. Nonswitchers (NS) remained on one aTNF throughout the study period (date of the first aT...
متن کاملRandomized trial of switching from prescribed non-selective non-steroidal anti-inflammatory drugs to prescribed celecoxib
Citation for published version: MacDonald, TM, Hawkey, CJ, Ford, I, McMurray, JJV, Scheiman, JM, Hallas, J, Findlay, E, Grobbee, DE, Hobbs, FDR, Ralston, SH, Reid, DM, Walters, MR, Webster, J, Ruschitzka, F, Ritchie, LD, Perez-Gutthann, S, Connolly, E, Greenlaw, N, Wilson, A, Wei, L & Mackenzie, IS 2016, 'Randomized trial of switching from prescribed non-selective non-steroidal anti-inflammator...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Science
سال: 2010
ISSN: 0036-8075,1095-9203
DOI: 10.1126/science.330.6007.1022-c